Research Group Leader
Sharma V, Lehmann T, Stuckas H, Funke L, and Hiller M #. Loss of INSL3 and RXFP2 genes in afrotheria shows that testicular descent is the ancestral condition in placental mammals. PLoS Biology 16(6), e2005293, 2018, some Press: New York Times, Smithsonian Magazine, Inside Science, Scienmag
Florio M, Heide M, Pinson A, Brandl H, Albert M, Winkler S, Wimberger P, Huttner WB #, Hiller M #. Evolution and cell-type specificity of human-specific genes preferentially expressed in progenitors of fetal neocortex. Elife, 7, 2018, F1000
Sharma V, Hecker N, Roscito JG, Foerster L, Langer BE, and Hiller M #. A genomics approach reveals insights into the importance of gene losses for mammalian adaptations. Nature Communications, 9(1), 1215, 2018
Nowoshilow S, Schloissnig S #, Fei JF, Dahl A, Pang AWC, Pippel M, Winkler S, Hastie AR, Young G, Roscito JG, Falcon F, Knapp D, Powell S, Cruz A, Cao H, Habermann B, Hiller M #, Tanaka EM #, Myers E. (2018) The axolotl genome and the evolution of key tissue formation regulators. Nature, 554(7690), 50-55.
Sharma V, Hiller M # (2017) Increased alignment sensitivity improves the usage of genome alignments for comparative gene annotation. Nucleic Acids Res, 45(14) 8369-8377.
Prudent X, Parra G, Schwede P, Roscito JG, Hiller M # (2016). Controlling for phylogenetic relatedness and evolutionary rates improves the discovery of associations between species’ phenotypic and genomic differences. Mol Biol Evol, 33(8), 2135-5.
See also MBE News.
Hiller M #, Schaar BT, Indjeian VB, Kingsley DM, Hagey LR, and Bejerano G. (2012): A “forward genomics” approach links genotype to phenotype using independent phenotypic losses among related species. Cell Reports, 2(4), 817-823.
Read more on F1000 and HFSP
McLean CY, Bristor D, Hiller M, Clarke SL, Schaar BT, Lowe CB, Wenger AM, Bejerano G. (2010): GREAT improves functional interpretation of cis-regulatory regions. Nature Biotechnol., 28(5), 495-501
Hiller M #, Findeiss S, Lein S, Marz M, Nickel C, Rose D, Schulz C, Backofen R, Prohaska SJ, Reuter G and Stadler PF. (2009): Conserved Introns Reveal Novel Transcripts in Drosophila melanogaster. Genome Res. 19(7), 1289-1300
Hiller M*, Huse K*, Szafranski K, Jahn N, Hampe J, Schreiber S, Backofen R, and Platzer M. (2004): Widespread occurrence of alternative splicing at NAGNAG acceptors contributes to proteome plasticity. Nature Genet. 36(12), 1255-7
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