| A. Teitelbaum, V. Nenadovic, F. Barcelo, L. Garcia Dominguez, W. Kostelecki, J. Brian, J.L. Perez Velazquez. Current perspectives on brain activity propose that the coordinated integration of transient activity patterns in distinct brain regions is essential for information processing and that widespread activation of brain areas is thought to give rise to conscious processing. It is thus conceivable to hypothesise that the coordinated activity patterns are different between healthy and pathological conditions. We have evaluated the patterns of brain synchronised activity in terms of the magnitude of the synchrony and the spatio-temporal fluctuations in healthy conditions as well as in autism and altered states of consciousness (traumatic brain injury, coma, sleep). The findings support the notion that specific patterns of correlated activity underlie cognitive tasks and, more specifically, the determination of the spatio-temporal fluctuations in synchronization may be of clinical interest to assess brain pathological states and the patients' prognosis. |
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