Short-term depression and facilitation are found in many synapses. Their possible biological function is still a subject of intense research. Here I present some results on a phenomenological model that combines short-term facilitation and depression and discuss in particular how the spectral statistics of the presynaptic input changes due to synaptic plasticity. I also show that in conjunction with disynaptic inhibition synaptic plasticity can lead to a nonmonotonic dependence of the firing rate on input rate. The implication of this relationship for reafference suppression in the electrosensory system of weakly electric fish are also discussed. |