| Cell adhesion moities (CAMs) or gap junctions are proteins that provide the basis of intercellular adhesion. It is observed that in the contact domain between two cells there is a highly enhanced concentration of these objects. In the 1980's, Braun, Abner, and Owicki (BAO) suggested this CAM aggregation was driven by the intermembrane repulsions in the interstitial domain between adhesion sites. Subsequently together with R. Bruinsma and M. Goulian, we explored the BAO model in terms of the interplay between Helfrich fluctuations and 2d entropy of mixing. This talk will describe our model in the light of temperature renormalization and discuss recent extensions and simulations. |
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