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We used simple neuron models of different types to predict
neuronal activity during intracellular current injection.
Having previously used standard integrate-and-fire neurons
with adaptation,
and spike response models with sliding threshold,
we now show directly from experiments that a simple neuron model
should feature an exponential spike initation mechanism
combined with refractory effects.
The quality of the spike-by-spike prediction is scaled
by the intrinsic noisiness of the neuron.
[1] R. Jolivet, A. Rauch, H.-R. Lüscher and W. Gerstner (2006) Predicting spike timing of neocortical pyramidal neurons by simple threshold models Journal of Computational Neuroscience 21:35-49 [2] C. Clopath, R. Jolivet, A. Rauch, H.-R. Lüscher and W. Gerstner (2007) Predicting neuronal activity with simple models of the threshold type: Adaptive Exponential Integrate-and-Fire model with two compartments Neurocomputing 70:1668-1673, [3] L. Badel et al.,(2007), submitted. [4] R. Jolivet et al., (2007) submitted |
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