Response properties of reduced neuron models to fluctuating synaptic drive

Magnus Richardson

University of Warwick, Warwick Systems Biology Department, Coventry, U.K.

n experimental method will be described for extracting the non-linear I-V curve from intracellular-voltage data. The method provides empirical grounds for the choice of which non-linear integrate-and-fire model to use to model different classes of cortical cells. To complement the modelling of experiment, a rather simple method for generating solutions for the firing-rate modulation of any non-linear integrate-and-fire model, or recurrent network comprised of such model neurons, will also be described.

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