Download: pdf-file


Physical Principles of Protein Behavior in the Cell

International Workshop - October 26 - 30, 2009

Scientific coordinators:

Markus Porto (Technische Universität Darmstadt, Germany)
H. Eduardo Roman (Universitá di Milano-Bicocca, Italy)
Michele Vendruscolo (University of Cambridge, U.K.)

Organisation:

Claudia Poenisch (MPI für Physik komplexer Systeme, Dresden, Germany)

Proteins are involved in essentially all the biochemical reactions taking place in the cell, including those required for the control of gene expression, metabolism, transport, and enzymatic catalysis. The enormous complexity of the mechanisms of regulation of protein behaviour in the cell are being unraveled at an increasing pace. Much advance has been made in our understanding of the way in which the concentration, localization, and interactions are controlled within living cells. The introduction of novel experimental high-throughput techniques and theoretical methods of analysis have enabled the initial study of the networks of interacting molecules that underlie the functioning of the myriad biological pathways through which cells maintain homeostasis and promote development.

We aim at bringing together researchers from the major areas relevant to understanding protein behavior in the cell, including protein expression, localization, function, folding, and aggregation. Possible synergies between experimental, theoretical, computational, and statistical approaches are anticipated to take place on two main fronts. On the one hand, to improve our understanding of the physico-chemical basis of protein behavior, and, on the other hand, to suggest new methods for predicting and controlling it. When achieved, such synergies will provide an integrated view of the subject, and we envisage that our workshop will stimulate such an integration.


Invited speakers (to be confirmed):

Ruedi Aebersold (Switzerland) Alan R. Fersht (UK) Andreas Pluckthun (Switzerland)
Patrick Aloy (Spain) Judith Frydman (USA) Michael Schroeder (Germany)
Madan Babu Mohan (UK) F. Ulrich Hartl (Germany) Petra Schwille (Germany)
Sĝren Brunak (Denmark) Amnon Horovitz (Israel) Eugene Shakhnovich (USA)
Janusz M. Bujnicki (Poland) Eugene Koonin (USA) Giulio Superti-Furga (Austria)
Harmen Bussemaker (USA) Kathryn Lilley (UK) Gian Gaetano Tartaglia (UK)
Konrad Büssow (Germany) Nick Luscombe (UK) Salvador Ventura (Spain)
Fabrizio Chiti (Italy) Matthias Mann (Germany) Massimo Vergassola (France)
Richard N. Day (USA) Edward Marcotte (USA) Claus O. Wilke (USA)


Applications are welcome and should be made by using the application form on the conference web page. However, please note that the number of attendees is very limited. The registration fee is 100 Euro, costs for accommodation and meals will be covered by the Max Planck Institute. In exceptional cases, limited funding for travel expenses is available. Please note that childcare is available upon request.

Deadline for registration is June 30, 2009.



For further information please e-mail to: phppbc09mpipks-dresden.mpg.de