scientific program

SUNDAY (April 3)
MONDAY (April 4)
TUESDAY (April 5)
WEDNESDAY (April 6)
THURSDAY (April 7)
FRIDAY (April 8)




Sunday, April 3

18.00 - 20.00 Registration
19.00 - Reception with food and beverages
   
Monday, April 4

09.00 - 09.15 Jan-Michael Rost (Director MPI für Physik komplexer Systeme) &
  Scientific Coordinators
  Opening
   
  Lymphocyte homeostasis and diversity maintenance
   
09.15 - 09.55 Antonio Freitas (Institut Pasteur, Paris)
  Role of quorum-sensing mechanisms in lymphocyte homeostasis
   
09.55 - 10.35 Robin Callard (University College London)
  T cell homeostasis in health and disease
   
10.35 - 10.55 Coffee break
   
10.55 - 11.35 Vanessa Venturi (University of New South Wales)
  Evolution of an epitope-specific CD8+ T cell receptor repertoire across the lifespan
11.35 - 12.15 Benedict Seddon (Medical Research Council UK)
  Modelling diverse T cell responses to lymphopenia
   
12.15 - 13.00 Discussion: Homeostatic regulation
   
13.00 - 14.15 Lunch
   
  Model selection
   
15.20 - 16.00 Juliane Liepe (Imperial College London)
  Calibrating multi-scale models of macrophage dynamics
   
16.00 - 16.30 Coffee break
   
16.30 - 17.30
PICA11-Colloquium
  Andreas Radbruch (Deutsches Rheuma-Forschungszentrum Berlin)
  Modelling and experimentation: Approaching the complexity of the immune system
   
18.00 - 19.00 Supper
   
19.30 - 22.00 Poster session I (including beverages)
   
Tuesday, April 5

  Experimentally-based modelling
   
09.00 - 09.40 Thomas Höfer (Deutsches Krebsforschungszentrum Heidelberg)
  Experimentally-based modeling of proliferation and differentiation decisions in T cells
   
09.40 - 10.20 Phil Hodgkin (The Walter and Eliza Hall Institute of Medical Research, Parkville)
  An evolutionary theory to bind together our molecular, cellular and systems based understanding of the immune response
   
10.20 - 10.40 Coffee break
   
10.40 - 11.20 Jonathan Lindquist (Otto-von-Guericke Universität Magdeburg)
  Modeling T cell activation
   
11.20 - 12.00 Rob de Boer (Utrecht University)
  How to properly estimate cellular turnover rates from in vivo labeling data?
   
12.00 - 12.40 Ramit Mehr (Bar-Ilan University, Ramat-Gan)
  The complexity of natural killer cell repertoires
   
12.40 - 13.40 Lunch
   
  Multi-scale modelling
   
13.40 - 14.20 Jorge Carneiro (Instituto Gulbenkian de Ciência, Oeiras)
  Multiscale model regulatory T cell dynamics
   
14.20 - 15.00 Grégoire Altan-Bonnet (Memorial Sloan-Kettering Cancer Center, NY)
  Differential suppression of effector T cells by regulatory T cells derives from a highly-dynamic IL-2 tug-of-war
   
15.00 - 15.20 Coffee break
   
15.20 - 16.00 Ken Duffy (National University of Ireland, Maynooth)
  How many distinct heritable factors are required to explain correlation structures in proliferating lymphocytes?
   
16.00 - 16.40 Grant Lythe (University of Leeds)
  Timescales of the immune response
   
  Discussion
   
16.40 - 17.30 Multi-scale modeling - the naked truth
   
17.30 - 18.30 Supper
   
18.30 Tour of Dresden
   
   
Wednesday, April 6

  Immune responses against viruses
   
09.00 - 09.40 Vitaly Ganusov (University of Tennessee)
  Modeling control of viral infections by CD8 T cell response
   
09.40 - 10.20 Avidan Neumann (Bar-Ilan University)
  Understanding viral resistance evolution patterns with a multi-level viral dynamics model incorporating intra-cellular replication
   
10.20 - 10.25
Group photo
  (to be published on the website)
   
10.25 - 10.40 Coffee break
   
10.40 - 11.20 Ruy Ribeiro (Los Alamos National Laboratory )
  How fast are virions cleared from the body?
   
11.20 - 12.00 Steven Kleinstein (Yale University School of Medicine)
  Unraveling antiviral regulatory networks using systems biology
   
12.00 - 12.30 Discussion
12.30 - 13.30 Lunch
14.00 - 22.00 Excursion and Conference Dinner - Königstein
   
   
Thursday, April 7

  Humoral immune response and affinity maturation
   
09.00 - 09.40 Deborah Dunn-Walters (King's College London)
  B cell repertoire changes in ageing
   
09.40 - 10.20 José Faro (Universidade de Vigo)
  Reassessing the oligoclonality concept of germinal centers
   
10.20 - 10.40 Coffee break
   
10.40 - 11.20 Michael Meyer-Hermann (Helmholtz Zentrum für Infektionsforschung, Braunschweig)
  How innate immunity controls adaptive antibody responses
   
11.20 - 12.00 Uri Hershberg (Drexel University, Philadelphia)
  B cell repertoire movement in the codon network - Towards a complex systems model of B cell repertoire diversity and its evolution
   
12.00 - 12.40 Michal Or-Guil (Humboldt Universität zu Berlin)
  Aspects of modelling antibody affinity maturation in germinal centers
   
12.40 - 13.40 Lunch
   
  TCR-receptor signalling and T cell activation
   
13.40 - 14.20 Raquel Blanco (Consejo Superior de Investigaciones Científicas, Madrid)
  Conformational change and cooperartivity in the TCR
   
14.20 - 15.00 Arup Chakraborty (Massachusetts Institute of Technology, Cambridge)
  How T cells see antigen: from statistical mechanics to human disease
   
15.00 - 15.40 Benedita Rocha (Institut Necker, Paris)
  The complexity of gene expression during CD8 activation in immune responses
   
15.40 - 16.00 Coffee break
   
16.00 - 16.40 Ria Baumgraß (Deutsches Rheuma-Forschungszentrum Berlin - DRFZ)
  Quantitative single cell analysis of transcription factor expression and activation to discover limiting factors for Th cell activation
   
16.40 - 17.20 Ellen Baake (Universität Bielefeld)
  Negative selection of T-cells: The importance of being rare
   
17.20 - 18.00 Dagmar Iber (ETH Zürich)
  Activation by trans auto-activation permits binding discrimination at high receptor occupancy
   
  Discussion
   
18.00 - 19.00 Large scale retrieval of experimental data: strategies for experimental design, data storage, and modelling
19.00 - 20.00 Supper
   
Friday, April 8

  Clinical and medical immunology
   
09.00 - 09.40 Sebastian Gerdes (Technische Universität Dresden)
  Can polyclonality prevent the outbreak of leukemia?
   
09.40 - 10.20 Sergey Deyev (Russian Academy of Sciences)
  Immunotargeting of nanoconstructs for cancer imaging and therapy
   
10.20 - 10.40 Coffee break
   
10.40 - 11.20 Stefan Bornholdt (Universität Bremen)
  Competing for the host: The dynamics of multiple epidemics
   
11.20 - 12.00 Pasquale Maffia (University of Glasgow)
  Real time imaging of immune response in atherosclerosis and stroke
   
12.00 - 12.10 Closing remarks
   
12.10 Lunch
   


Last updated: March 24, 2011