Preliminary Program
| Sunday, July 15 | |
| 18:00 - 20:00 | Registration |
| 19:00 - 21:00 | Welcome reception |
| Monday, July 16 | |
| 09:00 - 09:25 | Holger Kantz (MPIPKS Dresden) & Scientific coordinators |
| Opening | |
|
Allostery |
|
| 09:25 - 09:30 | Opening |
| Chairperson: Ruth Nussinov | |
| 09:30 - 10:15 | Dorothee Kern (Brandeis University, Waltham) |
| Choreographing an enzyme's dance - Dynamics during catalysis | |
| 10:15 - 11:00 | Igor Berezovsky (University of Bergen) |
| Molecular basis of allosteric regulation and communication | |
| 11:00 - 11:30 | Coffee break |
| 11:30 - 12:15 | Thomas Weikl (MPI of Colloids and Interfaces, Potsdam) |
| Conformational selection and induced changes in protein function |
|
| 12:15 - 14:25 | Lunch |
|
Allostery |
|
| 14:25 - 14:30 | Opening |
| Chairperson: Igor Berezovsky | |
| 14:30 - 15:15 | Amnon Horovitz (Weizmann Institute, Rehovot) |
| Allostery in GroEL: From mechanism to function |
|
| 15:15 - 16:00 | Coffee break |
|
DYPROT12 Colloquium Chairperson: Michael Hiller (MPIPKS Dresden) |
|
| 16:30 - 17:30 | Ruth Nussinov (SAIC-Frederick) |
| Networks in the cell: Structural networks of signaling pathways on the proteome scale |
|
| 17:30 - 18:30 | Discussion I - From single sequence-structure-function to dynamic ensembles |
| 18:30 - 19:30 | Dinner |
| Tuesday, July 17 | |
|
Self-assembly |
|
| 09:00 - 09:05 | Opening |
| Chairperson: Devarajan Thirumalai | |
| 09:05 - 09:50 | Simon Alberti (MPI for Molecular Cell Biology and Genetics, Dresden) |
| Protein self-assembly and the formation of cellular structures and memories |
|
| 09:50 - 10:35 | Petra Schwille (BIOTEC, Dresden) |
| Spatial cues for protein self-organization |
|
| 10:35 - 11:20 | Joseph Marsh (MRC Laboratory of Molecular Biology, Cambridge) |
| Subunit flexibility facilitates protein complex assembly and evolution |
|
| 11:20 - 11:45 | Coffee break |
|
Aggregation |
|
| 11:45 - 11:50 | Opening |
| Chairperson: Simon Alberti | |
| 11:50 - 12:35 | Fabrizio Chiti (Università di Firenze) |
| The structural determinants of protein oligomer toxicity | |
| 12:35 - 12:55 | Francesco Bemporad (University of Cambridge) |
| Characterizing intermolecular interactions that initiate native-like protein aggregation |
|
| 12:55 - 14:30 | Lunch |
|
Disorder |
|
| 14:30 - 14:35 | Opening |
| Chairperson: Modesto Orozco | |
| 14:35 - 15:20 | Vladimir Uversky (University of South Florida, Tampa) |
| Intrinsic disorder-based interactions and their modulators | |
| 15:20 - 16:05 | Vincent Hilser (Johns Hopkins University, Baltimore) |
| Biological ensembles are poised to respond | |
| 16:05 - 16:30 | Coffee break |
| Chairperson: Vladimir Uversky | |
| 16:30 - 17:15 | Marija Buljan (MRC Laboratory of Molecular Biology, Cambridge) |
| Tissue-specific splicing rewires protein interaction networks | |
| 17:15 - 18:00 | Monica Fuxreiter (University of Debrecen) |
| Fuzziness: Ambiguity in protein interactions | |
| 18:00 - 18:45 | Discussion II - Structural disorder and protein complexity |
| 18:45 - 20:30 | Dinner |
| 20:30 - 22:00 |
Poster session I |
| Wednesday, July 18 | |
|
Computational methods |
|
| 09:00 - 09:05 | Opening |
| Chairperson: Gunnar Schröder | |
| 09:05 - 09:50 | Modesto Orozco (Institute for Research in Biomedicine, Barcelona) |
| New approaches for the study of protein dynamics in the post-genome scenario | |
| 09:50 - 10:35 | Martin Zacharias (Technische Universität München) |
| Accounting for conformational changes during protein-protein docking | |
| 10:35 - 11:00 | Coffee break |
| Chairperson: Arne Elofsson | |
| 11:00 - 11:45 | Devarajan Thirumalai (University of Maryland) |
| Allosteric transitions in molecular machines | |
| 11:45 - 13:30 | Lunch |
| 13:30 - 19:00 | Conference Excursion to Meissen |
| 19:00 - 22:00 | Conference Dinner |
| Thursday, July 19 | |
|
Evolution: Structure-function relationship |
|
| 09:00 - 09:05 | Opening |
| Chairperson: Amnon Horovitz | |
| 09:05 - 09:50 | Garegin Papoian (MPIPKS Dresden) |
| Energy landscapes view of protein functional dynamics | |
| 09:50 - 10:35 | Michael Lässig (Universität zu Köln) |
| Protein evolution in the human influenza virus | |
| 10:35 - 11:00 | Coffee break |
| Chairperson: Joseph Marsh | |
| 11:00 - 11:45 | Christine Orengo (University College London) |
| Evolution of functions in domain structures - exploring shifts in functional sites | |
| 11:45 - 12:05 | Arne Elofsson (Stockholm University) |
| Disorder regions are indel hotspots | |
| 12:05 - 12:25 | Inmaculada Yruela (Consejo Superior de Investigaciones Científicas, Zaragoza) |
| Protein disorder in plants: A view from the chloroplast | |
| 12:25 - 14:00 | Lunch |
|
Evolution of protein structures and dynamics |
|
| 14:00 - 14:05 | Opening |
| Chairperson: Christine Orengo | |
| 14:05 - 14:50 | Nick Grishin (The University of Texas Southwestern Medical Center, Dallas) |
| Evolution of protein spatial structures | |
| 14:50 - 15:10 | Rachel Kolodny (University of Haifa) |
| A bird's eye view of protein structure space | |
| 15:10 - 15:55 | Erich Bornberg-Bauer (Universität Münster) |
| Escape from adaptive conflict in protein evolution follows from weak functional trade-offs and mutational robustness | |
| 15:55 - 16:20 | Coffee break |
| Chairperson: Erich Bornberg-Bauer | |
| 16:20 - 16:40 | Tobias Sikosek (Universität Münster) |
| Bi-stability in proteins as a potential evolutionary response to adaptive conflicts | |
| 16:40 - 17:00 | Jessica Siltberg-Liberles (University of Wyoming, Laramie) |
| Evolutionary dynamics of conformational flexibility in the prion protein and its remote homologs | |
| 17:00 - 17:20 | Edvin Fuglebakk (University of Bergen) |
| Characteristics of structural flexibility in protein evolution | |
| 17:20 - 18:30 | Discussion III - Evolution of protein structures: Do we need a new view of protein structure space? |
| 18:30 - 20:30 | Dinner |
| 20:30 - 22:00 |
Poster session II |
| Friday, July 20 | |
|
Folding |
|
| 09:00 - 09:05 | Opening |
| Chairperson: Monika Fuxreiter | |
| 09:05 - 09:50 | Gunnar Schröder (Forschungszentrum Jülich) |
| Protein structure and dynamics from low-resolution data | |
| 09:50 - 10:10 | Oxana Galzitskaya (Russian Academy of Sciences, Pushchino) |
| Influence of organization of native structure on its folding: Modeling of protein folding | |
| 10:10 - 10:30 | Antonija Kuzmanic (Max F. Perutz Laboratories, Vienna) |
| On the contribution of linear correlations to quasi-harmonic conformational entropy in proteins | |
| 10:30 - 11:00 | Coffee break |
| 11:00 - 11:45 | Anna Tramontano (Sapienza University, Rome) |
| Protein structure prediction and analysis: The case of antibodies | |
| 11:45 - 12:30 | Discussion IV and conclusions - Modelling dynamic proteins: Are allostery and structural disorder two sides of the same coin? |
| 12:30 | Lunch and departure |
Last update: 18/07/2012
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