Program

→ Please click on the title to the see the abstract (if available).

Sunday, October 25  
   
18:00 - 20:00 Registration
   
19:00 - 21:00 Welcome reception
   
   
Monday, October 26  
   
08:45 - 09:00 Frank Jülicher (Director MPIPKS) & Scientific Coordinators
  Opening
   
  Proteomics I - Chair Kathryn Lilley
   
09:00 - 09:05 Chair: Introduction to the session
   
09:05 - 09:55 Ruedi Aebersold (ETH Zurich)
  Mass spectrometric methods to measure dynamic protein interaction networks
   
09:55 - 10:45 Konrad Büssow (Helmholtz Centre for Infection Research)
  Systematic expression of mammalian proteins for structural studies
   
10:45 - 11:15 Coffee break
   
11:15 - 12:05 Madan Babu Mohan (University of Cambridge)
  Intrinsically unstructured proteins: Regulation and disease
   
12:05 - 12:55 Petra Schwille (Technical University Dresden)
  Single molecule analysis of morphogen spreading in living embryos
   
12:55 - 13:00 Concluding discussion
   
13:00 - 14:10 Lunch
   
  Protein evolution - Chair Edward Marcotte
   
14:10 - 14:15 Chair: Introduction to the session
   
14:15 - 15:05 Eugene Shakhnovich (Harvard University)
  Bridging scales in biology: From atoms to organisms
   
15:05 - 15:30 Ugo Bastolla (Universidad Autonoma Madrid)
  Extreme mutation bias favors protein folding stability in the evolution of small populations
   
15:30 - 15:55 Andrey Cherstvy (Research Center Jülich)
  Facilitated protein diffusion on DNA and DNA-protein electrostatic recognition
   
15:55 - 16:00 Concluding discussion
   
16:00 - 16:30 Coffee break
   
16:30 - 17:30 PHPPBC09 Colloquium - Chair Frank Jülicher (MPIPKS)
  Judith Frydman (Stanford University)
  Molecular origami: Protein folding and misfolding in health and disease
   
19:00 - 20:30 Dinner
   
20:30 - ... Discussion session
   
   
Tuesday, October 27  
   
  Modeling cell behavior - Chair Michael Schroeder
   
09:00 - 09:05 Chair: Introduction to the session
   
09:05 - 09:55 Stephan Grill (MPIPKS Dresden)
  Active forces and flows in the establishment of cellular polarity
   
09:55 - 10:45 Gian Gaetano Tartaglia (University of Cambridge)
  Towards quantitative predictions in cell biology using chemical properties of proteins
   
10:45 - 11:15 Coffee break
   
11:15 - 12:05 Harmen Bussemaker (Columbia University)
  Learning mechanistic models of gene expression regulation from natural sequence variation
   
12:05 - 12:30 Christof Winter (Technical University Dresden)
  Predicting protein-RNA interactions in diabetes - How a novel computational method helps to identify regulators of insulin secretion
   
12:30 - 12:55 Alessandro Barducci (ETH Zurich)
  Extending the capabilities of all-atom molecular dynamics simulations: A well-tempered approach to protein conformational dynamics
   
12:55 - 13:00 Concluding discussion
   
13:00 - 14:10 Lunch
   
  Protein folding and misfolding I - Chair Amnon Horovitz
   
14:10 - 14:15 Chair: Introduction to the session
   
14:15 - 15:05 Salvador Ventura (Universitat Autònoma de Barcelona)
  Towards a model of protein aggregation in bacteria
   
15:05 - 15:30 Fabio Pichierri (Tohoku University)
  What is the relationship between electronic structure and protein dynamics?
   
15:30 - 15:55 Anne Tuukkanen (Technical University Dresden)
  A novel approach to structural modelling of large protein complexes
   
15:55 - 16:25 Coffee break
   
16:25 - 16:50 Raul Mendez (Centre for Molecular Biology, Madrid)
  TNM: A new coarse-grained elastic network model in torsional space
   
16:50 - 17:15 Mark Tsechansky (University of Texas at Austin)
  Protein punctation in yeast - A generic protein aggregation phenomenon with evolutionary implications
   
17:15 - 17:20 Concluding discussion
   
19:00 - 20:30 Dinner
   
20:30 - ... Poster session
   
   
Wednesday, October 28  
   
  Proteomics II - Chair Konrad Büssow
   
09:00 - 09:05 Chair: Introduction to the session
   
09:05 - 09:55 Kathryn Lilley (University of Cambridge)
  Using proteomics approaches to determine sub-cellular location of proteins
   
09:55 - 10:45 Matthias Mann (MPI for Biochemistry, Martinsried)
  Quantitative, large-scale phosphoproteomics to elucidate cellular signal processing
   
10:45 - 10:50 Group photo
  (to be published on the website)
   
10:50 - 11:15 Coffee break
   
11:15 - 12:05 Søren Brunak (Technical University of Denmark, Lyngby)
  Phenotype-specific protein network biology
   
12:05 - 12:10 Concluding discussion
   
12:10 - 13:45 Lunch
   
14:00 Excursion
  (guided tour at the Semper Opera, guided city tour incl. snack, visit of the Historic Green Vault)
   
19:30 Workshop Dinner at the restaurant ``Carolaschlösschen''
   
   
Thursday, October 29  
   
  Protein interaction - Chair Richard N. Day
   
09:00 - 09:05 Chair: Introduction to the session
   
09:05 - 09:55 Patrick Aloy (Institute for Research in Biomedicine, Barcelona)
  Structural systems biology: Modelling protein interactions and complexes
   
09:55 - 10:45 Andreas Plückthun (University of Zurich)
  Stable binding proteins by design and evolution: Towards a modular recognition code
   
10:45 - 11:15 Coffee break
   
11:15 - 12:05 Michael Schroeder (Technical University Dresden)
  Network compression: Theory, algorithms and applications in disease
   
12:05 - 12:55 Jacques Colinge (Research Center for Molecular Medicine, Vienna)
  t.b.a.
   
12:55 - 13:00 Concluding discussion
   
13:00 - 14:10 Lunch
   
  Protein expression - Chair Gian Gaetano Tartaglia
   
14:10 - 14:15 Chair: Introduction to the session
   
14:15 - 15:05 Nick Luscombe (European Bioinformatics Institute, Cambridge)
  Nucleoporins, chromosomal organisation and gene regulation
   
15:05 - 15:55 Claus O. Wilke (University of Texas at Austin)
  Mistranslation-induced protein misfolding as a dominant constraint on coding- sequence evolution
   
15:55 - 16:25 Coffee break
   
16:25 - 17:15 Richard N. Day (Indiana University School of Medicine, Indianapolis)
  Monitoring dynamic protein interactions in the living cell nucleus
   
17:15 - 18:05 Edward Marcotte (University of Texas at Austin)
  Insights from proteomics into cellular evolution and surprising disease models
   
18:05 - 18:10 Concluding discussion
   
19:00 - 20:30 Dinner
   
20:30 - ... Poster session
   
   
Friday, October 30  
   
  Protein folding and misfolding II - Chair Salvador Ventura
   
09:00 - 09:05 Chair: Introduction to the session
   
09:05 - 09:55 Daniel Müller (Technical University Dresden)
  Quantifying interactions guiding membrane protein folding, unfolding and function by single-molecule force spectroscopy and microscopy
   
09:55 - 10:20 Andrey Solov'yov (Frankfurt University)
  Statistical mechanics of polypeptide and protein folding in vacuum and water environment
   
10:20 - 10:45 Tihamer Geyer (Saarland University)
  Coarse grained simulations of a small peptide: Effects of finite damping and hydrodynamic interactions
   
10:45 - 11:15 Coffee break
   
11:15 - 12:05 Amnon Horovitz (Weizmann Institute of Science, Rehovot)
  Linking allostery in chaperonins to protein folding
   
12:05 - 12:20 Concluding discussion
   
12:20 - 12:25 Closing
   
12:30 Lunch
   
   



Last update: 29/10/2009