| 09:00 - 09:45 |
Encarnita Mariotti-Ferrandiz
(Sorbonne Université)
Identifying Blood T Cell Receptor Repertoire as Classifiers for Autoimmune and Inflammatory Diseases: lessons from a multi-disease study |
| 09:45 - 10:30 |
Tomer Hertz
(Ben Gurion University of the Negev)
HLA Escape and Exposure: A Balancing Act in Viral Evolution |
| 10:30 - 11:15 |
Coffee Break |
| 11:15 - 12:00 |
Jim Kaufman
(Yale University)
Evolution of the adaptive immune system of jawed vertebrates |
| 12:00 - 12:45 |
Jonathan Yewdell
(National Institute of Allergy and Infectious Diseases)
MHC I Peptide Generation Breaks the Law of Mass Action |
| 12:45 - 14:00 |
Lunch Break |
| 14:00 - 14:45 |
Andrew Sewell
(Cardiff University)
TBA |
| 14:45 - 15:30 |
David Klatzmann
(Sorbonne Université)
How specific is the T cell response in real life? |
| 15:30 - 16:15 |
Coffee Break |
| 16:15 - 17:00 |
Anastasia Minervina
(Fred Hutchinson Cancer Center)
Uneven TCR chain pairing constraints govern epitope recognition |
| 17:00 - 17:45 |
Christopher Boughter
(Takeda)
Lost in [Latent] Space: Understanding the Role of Embeddings in Repertoire Analysis |
| 18:00 - 20:00 |
Dinner |
| 20:00 - 22:00 |
Poster Session 1 (Odd Numbers) |
| 09:00 - 09:45 |
Rob de Boer
(Utrecht University)
Interpreting deuterium labeling data |
| 09:45 - 10:30 |
Michael Meyer-Hermann
(Helmholtz Centre for Infection Research)
Recent changes in textbook germinal centers |
| 10:30 - 11:15 |
Coffee Break + Group Photo (to be published on the website) |
| 11:15 - 12:00 |
Thomas Höfer
(DKFZ Heidelberg)
Clonal dynamics of CMV-specific NK cells |
| 12:00 - 12:45 |
Mélanie Prague
(Université de Bordeaux, Inria-Inserm)
Integrating high-dimension markers in mechanistic models to unveil humoral response to vaccination |
| 12:45 - 13:15 |
Pick Up Packed Lunch |
| 13:15 - 19:00 |
Social Program: Guided Hike in Saxon Switzerland |
| 19:00 - 22:00 |
Social Dinner: Altes Wettbüro |
| 09:00 - 09:45 |
Veit R. Buchholz
(DKFZ Heidelberg)
Stem-like lymphocytes at the origin of adaptive immune responses to infection and cancer |
| 09:45 - 10:30 |
Dirk Busch
(Technical University of Munich)
Predicting and engineering antigen-specific T cell receptors for clinical applications |
| 10:30 - 11:00 |
Coffee Break |
| 11:00 - 11:45 |
Frederik Graw
(Friedrich-Alexander-Universität Erlangen-Nürnberg/ Universitätsklinikum Erlangen)
Determining the spatio-temporal dynamics of immune responses |
| 11:45 - 12:30 |
Dominik Wodarz
(University of California San Diego)
In vivo evolutionary dynamics of HIV-1 in the follicular and extra-follicular compartments of the lymphoid tissues |
| 12:30 - 13:30 |
Lunch Break |
| 13:30 - 14:15 |
Luis Zapata Ortiz
(The Institute of Cancer Research)
Quantifying Immune Selection in Cancer through Immune dN/dS: A Predictive Biomarker of Response to Immunotherapy |
| 14:15 - 15:00 |
Rajat Varma
(AstraZeneca)
PD-1 blockade enhances T cell activation by reorchestrating CD28 and CTLA4 ligand interaction |
| 15:00 - 15:30 |
Coffee Break |
| 15:30 - 16:15 |
Johannes Huppa
(Charité Universitätsmedizin Berlin)
How T-cells recognize antigens – insights from molecular imaging |
| 16:15 - 18:00 |
Discussion |
| 18:00 - 20:00 |
Dinner |
| 20:00 - 22:00 |
Poster Session 2 (Even Numbers) |
| 09:00 - 09:45 |
Paul G. Thomas
(Fred Hutchinson Cancer Lab)
Functional avidity and sequence features define the breadth of TCR cross-reactivity |
| 09:45 - 10:30 |
Benedict Seddon
(Medical Research Council UK)
Ontogeny of Regulatory T cells in Health and Malignant Disease |
| 10:30 - 11:15 |
Coffee Break |
| 11:15 - 12:00 |
Thorsten Prüstel
(National Institutes of Health)
Stochastic spatial modeling of signaling processes at cell-cell contacts and T cell receptor |
| 12:00 - 12:45 |
Grant Lythe
(University of Leeds)
T-cell repertoires and cross-reactivity |
| 12:45 - 14:00 |
Lunch Break |
| 14:00 - 16:00 |
Discussion & Closing/Farewell |